Prenatal screening program

Prenatal Screening Portal Resources
The page includes California Prenatal Screening (PNS) Program resources related to the
CalGenetic Portal.
On this page
- CalGenetic Portal Training Videos
- cfDNA Laboratory Instructions
- Provider Access to the CalGenetic Portal Chart
- Outcome of Pregnancy
- Portal Guidance and Links
- Outcome of Pregnancy FAQ
CalGenetic Portal Training Videos
Prenatal care providers and their staff have access to four videos below that provide step-by-step instructions for using the CalGenetic Portal to create a profile and view prenatal screening results for the California Prenatal Screening (PNS) Program. The videos explain how to do the following:
- Providers can create, access, and manage their user profile
- Providers create and manage their delegates’ access
- All users search, view, and download prenatal screening results
- Delegates create and access their user profile once an invitation from their managing provider is received
For questions, comments, or help regarding your CalGenetic Portal account, please send us an email at
pns@cdph.ca.gov with your username and any screenshots of error pages.
Please visit our
CalGenetic YouTube Playlist to access full-screen versions of the following embedded videos.
| Preview |
Description |
Intended Audience |
|---|---|---|
|
|
Title: CalGenetic Portal: User Access and Profile Management for Licensed Clinicians Published: 8/10/2022 Duration: 10:14 Description: This video provides instructions on how to create a new account, manage your profile demographics, and associated facilities. |
For: Prenatal care providers*
Note: The ‘Your Profile’ page will only be visible to Physicians, Osteopaths, Physicians Assistants, Licensed Midwives, Nurse Midwives, and Nurse Practitioners
|
|
|
Title: CalGenetic Portal: Manage Delegates Published: 8/6/2022 Duration: 9:49 Description: This video provides instructions to add, edit, and renew delegates, and how to remove delegate access rights. |
For: Physicians, Osteopaths, Physicians Assistants, Licensed Midwives, Nurse Midwives, and Nurse Practitioners |
|
|
Title: CalGenetic Portal: Search, View, and Download Results Published: 5/6/2022 Duration: 5:36 Description: This video provides instructions on how to Search, View, and Download Screening Results. |
For: Prenatal care providers* |
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Title: CalGenetic Portal: Access Delegate Account, Search, View, and Download Results Published: 5/6/2022 Duration: 7:26 Description: This video provides instructions for delegates to access their account and how to search, view, and download screening results. Authorization to use portal is based on Provider license and delegation. |
For: Delegates (staff) |
|
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Title: CalGenetic Portal: Submit Orders Published: 8/29/2022 Duration: 10:08 Description: This video provides instructions to submit orders on the CalGenetic Portal. |
For: Prenatal care providers* |
Recorded Webinar Training Video
CalGenetic Portal: New Features and Additional Training (webinar recorded January 25, 2023)
| Preview | Description |
|---|---|
|
|
Title: CalGenetic Portal: New Features and Additional Training
Published: 1/30/2023
Duration: 18:10 |
If you are having difficulty accessing this content, please contact CDPH at
GDSP.Communications@cdph.ca.gov to request this information in an alternate format.
PNS Program Changes
The PNS Program added cfDNA Screening in 2022 as a primary screening test and now allows for screening test ordering through the
CalGenetic Portal. Please see the PNS Program Provider FAQ web page for more information. Summary of Prenatal Screening Program Changes (PDF, 2 pages)
cfDNA Laboratory Instructions and FAQs
Natera
Quest
-
cfDNA Laboratory Instructions: Quest Diagnostics (PDF)
-
cfDNA Laboratory Additional Information: Quest Diagnostics (PDF)
Revvity
-
cfDNA Laboratory Instructions: Revvity (PDF)
- cfDNA Laboratory Additional Information: Revvity (PDF)
Provider Access to the CalGenetic Portal Chart
The chart below shows access to the CalGenetic portal, by profession.
|
Professions |
All access with license verified by IDEAL* |
Can access results as licensed users? |
Can place orders as licensed users? |
Can place orders as delegates? |
Can add delegates? |
|---|---|---|---|---|---|
| Physicians and Surgeons |
Yes |
Yes |
Yes |
- |
Yes |
| Osteopathic Physicians and Surgeons |
Yes |
Yes |
Yes |
- |
Yes |
| Licensed Midwife |
Yes |
Yes |
Yes |
- |
Yes |
| Physician Assistant |
Yes |
Yes |
Yes |
- |
Yes |
| Nurse Midwife |
Yes |
Yes |
Yes |
- |
Yes |
| Nurse Practitioner |
Yes |
Yes |
Yes |
- |
Yes |
| Registered Nurse |
Yes |
Yes |
- |
Yes |
No |
| Temporary Registered Nurse License |
Yes |
Yes |
- |
Yes |
No |
| Clinician Nurse Specialist |
Yes |
Yes |
- |
Yes |
No |
| Public Health Nurse |
Yes |
Yes |
- |
Yes |
No |
| Genetic Counselors |
- |
Yes |
- |
Yes |
No |
| Postgraduate Training License |
Yes |
Yes |
Yes |
No |
Yes |
| Office and Medical Assistants |
- |
- |
- |
Yes |
No |
* Interoperability Development Effort to Authenticate Licensees (IDEAL) is used by Medical Board of California to authenticate and support access to the CalGenetic Portal
Note: Delegates are all staff members, including office and medical assistants, that a licensed clinician (MD/DO) allows access to the CalGenetic Portal. Delegates generally do not have a professional license and therefore do not go through IDEAL verification on the CalGenetic Portal.
Outcome of Pregnancy
The Confidential Report of an Outcome of Pregnancy collects information on pregnancy and the outcome of pregnancy from healthcare providers who cared for a birthing parent with services related to prenatal screening. The California Code of Regulations (Title 17, Section 6527) require that this information be provided because it is essential to the analysis of the effectiveness of the policies and practices adopted by the California Prenatal Screening Program at the Genetic Disease Screening Program (GDSP).
It is mandatory that healthcare professionals completing this report provide complete and accurate information. The records maintained by GDSP are confidential as defined in Civil Code 1798.3 and are exempt from access by any individual except licensed medical personnel designated by the subject. It will be used for public health surveillance, Prenatal Screening Program evaluation, and special studies as defined in Health and Safety Code 100330. It is permitted under the Health Insurance Portability and Accountability Act (HIPAA) regulations.
GDSP has conducted the Confidential Report of an Outcome of Pregnancy survey for more than two decades. In December 2024, GDSP launched a
secure online portal where the Confidential Report of an Outcome of Pregnancy can be completed and submitted online.
Portal Guidance and Links
Note: Outcome of Pregnancy Portal web page and Prenatal Screening Results Portal web page now redirect to this web page.
Outcome of Pregnancy FAQ
The portal is designed for healthcare providers to complete and submit the Confidential Report of an Outcome of Pregnancy online.
Healthcare providers who cared for a birthing parent with services related to prenatal screening have access to the portal. First-time users are required to register with an email address.
Multifactor authentication (MFA) is an authentication method that requires users to verify identity using multiple independent methods. Instead of just asking for a username and password, MFA implements additional credentials. You will need to have a phone to access the portal. The portal will send you a text or call you upon each login as a second level of security authentication to verify your identity. Your phone number is entered at the time of account creation. If you get a new phone but keep the same phone number, your MFA will still work seamlessly. If you get a new phone number, you will need to contact GDSP at
In general, the confidential reports are sent to the prenatal providers for all pregnancies with screen-positive results, for a subsample of 1% of all screen-negative results, and for pregnancies with selected prenatal screening results (such as cfDNA low fetal fraction) with a potentially increased risk for neural tube defects and/or chromosomal abnormalities.
The confidential reports are sent out approximately 60 days following the expected date of delivery.
After the first email request with the subject line “Please Complete a Confidential Report on an Outcome of Pregnancy” has gone out, if no report is submitted on the portal, the reminder requests will be sent 30 days and 60 days after the initial request.
The requested information can be found in birthing parent’s medical records on the index pregnancy. Newborn’s medical records may also have the requested information if available.
Yes, please confirm this in the portal so that a ‘Second Request’ does not have to be sent to you. You will have a chance to enter another health provider’s information in the portal. The portal will then lead you to submission page without going through other questions.

