healthcare-associated infections (hai) program
Carbapenemase-producing Organisms (CPOs)
Prevention & Response
Find resources for preventing spread and responding to cases and outbreaks of carbapenemase-producing organisms (CPOs), including on screening, infection prevention and control measures, and investigation.
Prevention & Response Guidance Documents
- CPO Investigation & Response Quicksheet, Screening Decision Tree and Response Phases (PDF)
- CPO Quicksheet only (PDF)
- CPO Regional Phased Prevention and Response Strategy (PDF)
- CPO Screening Decision Tree (PDF) for guiding colonization testing recommendations in healthcare facilities
- Algorithm for Prioritizing Carbapenemase Testing (PDF) of carbapenem-resistant organisms.
- Cohorting Guidance (PDF) and Cohorting Guidance for Skilled Nursing Facilities (PDF) for patients or residents with multidrug-resistant organisms.
- Guidance for Short-stay Acute Care Hospitals on the Duration of Contact Precautions (PDF) for patients colonized or infected with a carbapenem-resistant organism or CPO
- Interfacility Transfer Communications Guide
Infection Prevention & Control Resources
Prevention & Response Webinars
- Best Practices for SNFs in Accepting Residents with MDROs – 2/15/24
- CDC Simplifying Carbapenem-resistant Organisms – 2022
- CPOs: CDPH Laboratory and Epidemiology Updates – 5/14/24
- CPOs: Guidance for Reporting and Containment – 9/29/22
- Slides (PDF) and Recording (opens in YouTube)
- The Role of Carbapenemase Testing in Clinical Practice – 12/6/22
- Slides (PDF) and Recording (opens in YouTube)
- Other Prevention & Response Webinars
Other Prevention & Response Resources
Find Additional CDPH Resources
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